ANCA - Serine Proteinase 3 (c-ANCA) - Serum

ANCA - Serine Proteinase 3 (c-ANCA) - Serum

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Helps to detect and diagnose certain forms of autoimmune vasculitis, including granulomatosis with polyangiitis (Wegener granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome).?

This Test Includes

C-ANCA (PR3)

Test Instructions

Total parameters available: 1

Parameter Names:

  • ANCA - Serine Proteinase 3 (c-ANCA) - Serum

Test Instructions/Precautions:

  • Alcohol: Please abstain from alcohol before the test
  • Medication :Any pre-existing medication should only be stopped after consultation with the referring Physician
  • Fluids Allowed : Water only

Reports

Soft Copy (Portal/Email) : If the sample is collected before 12 noon then the report will get delivered as per Reporting Time / Maximum TAT (Turn Around Time) indicated with the test. For samples collected after 12 Noon, 12 hours may be added to the Report Turn Around TimeHard Copy : Delivered at home upon request. A small convenience fee may apply.

Why it is Done

  • To help detect, aid in the diagnosis of, and sometimes monitor certain forms of the autoimmune disorder systemic vasculitis (inflammation of blood vessels).
  • To help distinguish between Crohn disease (CD) and ulcerative colitis (UC), the two most common types of inflammatory bowel disease (IBD); as an adjunct to other IBD testing.

What is this test

Myeloperoxidase or perinuclear antinuclear cytoplasmic antibody is useful to detect several types of Systemic necrotising vasculitis such as Microscopic polyarteritisand Crescentic glomerulonephritis. p-ANCA is found commonly in Churg Strauss Syndrome and 50% of patients with Ulcerative colitis.