Alpha -1 Antitrypsin (AAT) - Serum

Alpha -1 Antitrypsin (AAT) - Serum


Alpha-1 antitrypsin (AAT) testing is used to help diagnose alpha-1 antitrypsin deficiency as the cause of early chronic obstructive pulmonary disease (COPD) when a person does not have obvious risk factors such as smoking or exposure to lung irritants such as dust and fumes. It may also be used when someone has asthma that obstructs his or her breathing, even after treatment.

This Test Includes

Alpha - 1 Antitrypsin (AAT)

Test Instructions

Total parameters available: 1

Parameter Names:

  • Alpha -1 Antitrypsin (AAT) - Serum

Test Instructions/Precautions:

  • Alcohol: Please abstain from alcohol before the test
  • Medication :Any pre-existing medication should only be stopped after consultation with the referring Physician
  • Fluids Allowed : Water only


Soft Copy (Portal/Email) : If the sample is collected before 12 noon then the report will get delivered as per Reporting Time / Maximum TAT (Turn Around Time) indicated with the test. For samples collected after 12 Noon, 12 hours may be added to the Report Turn Around TimeHard Copy : Delivered at home upon request. A small convenience fee may apply.

Why it is Done

To help diagnose the cause of early onset emphysema and/or liver dysfunction; to establish the risk of emphysema and/or liver disease due to alpha-1 antitrypsin deficiency and determine the likelihood that children might inherit the risk.

What is this test

More than 40 phenotypes of Alpha -1 Antitrypsin (AAT) exist. The inherited deficiency seen most often as the ZZ, SS & SZ phenotypes is associated with Neonatal hepatitis & Infantile cirrhosis.