IGF-1 is a primary mediator of the effects of growth hormone (GH).Growth hormone is made in the anterior pituitary gland, is released into the blood stream, and then stimulates the liver to produce IGF-1. low levels of GH (which can be normal) mean the pituitary gland is not working correctly.
This Test Includes
Insulin-Like Growth Factor-I (IGF-I)
Total parameters available: 1
Soft Copy (Portal/Email) : If the sample is collected before 12 noon then the report will get delivered as per Reporting Time / Maximum TAT (Turn Around Time) indicated with the test. For samples collected after 12 Noon, 12 hours may be added to the Report Turn Around TimeHard Copy : Delivered at home upon request. A small convenience fee may apply.
Why it is Done
To help diagnose growth hormone (GH) deficiency or, less commonly, growth hormone excess; to evaluate pituitary function; to monitor the effectiveness of GH treatment.
What is this test
Insulin-like growth factor-1 (IGF-1) is a hormone that, along with growth hormone (GH), helps promote normal bone and tissue growth and development. The test measures the amount of IGF-1 in the blood.
IGF-1 is produced by the liver and skeletal muscle as well as many other tissues in response to GH stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. Since GH is released into the blood in pulses throughout the day, it is difficult to interpret the results from a single GH test. IGF-1 mirrors GH excesses and deficiencies, but unlike GH, its level is stable throughout the day. This makes IGF-1 a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess.